Browsing by Author "AVERKIOU, MICHALAKIS A."
Now showing items 1-20 of 39
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Accurate measurement of microbubble response to ultrasound with a diagnostic ultrasound scanner
Keravnou, Christina; Mannaris, Christophoros; AVERKIOU, MICHALAKIS A. (2015)Ultrasound and microbubbles are often used to enhance drug delivery and the suggested mechanisms are extravasation and sonoporation. Drug delivery schemes with ultrasound and microbubbles at both low and high acoustic ...
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Automatic dissociation between microvasculature and larger vessels for ultrasound contrast imaging
Perperidis, Antonios; Thomas, David; AVERKIOU, MICHALAKIS A.; Duncan, Colin; McNeilly, Alan; Butler, Mairead; Sboros, Vassilis (2014)
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Automatic respiratory gating for perfusion quantification of DCEUS
Christofides, Damianos; AVERKIOU, MICHALAKIS A.; Leen, Edward (2013)A novel automatic respiratory gating (ARG) algorithm for ultrasound is presented. The ARG algorithm was applied on dual contrast imaging (contrast/tissue) loops in order to remove respiratory motion artifacts from dynamic ...
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Contrast-enhanced 3D ultrasound in the radiofrequency ablation of liver tumors
Leen, Edward; Kumar, Senthil; Khan, Shahid A.; Low, Gavin; Ong, Keh Oon; Tait, Paul; AVERKIOU, MICHALAKIS A. (2008)Liver metastases and hepatocellular carcinomas are two of the most common causes of cancer deaths in the world. Radiofrequency ablation (RFA) is a well recognized, effective and minimally invasive means of treating malignant ...
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Dose-dependent artifact in the far wall of the carotid artery at dynamic contrast-enhanced US
Thapar, A.; Shalhoub, J.; AVERKIOU, MICHALAKIS A.; Mannaris, C.; Davies, A. H.; Leen, E. L.; Thapar, Ankur; Shalhoub, Joseph; AVERKIOU, MICHALAKIS A.; Mannaris, Christophoros; Davies, A. H.; Leen, Edward L. S. (2012)Purpose: To quantify a pseudoenhancement phenomenon observed during dynamic contrast material-enhanced ultrasonography (US) of the carotid artery, both in vitro and in vivo.Materials and Methods: Ethical approval was ...
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Dynamic contrast enhanced ultrasound assessment of the vascular effects of novel therapeutics in early stage trials
Leen, Edward; AVERKIOU, MICHALAKIS A.; Arditi, Marcel; Burns, Peter; Bokor, Daniela; Gauthier, Thomas; Kono, Yuko; Lucidarme, Olivier (2012)Imaging is key in the accurate monitoring of response to cancer therapies targeting tumour vascularity to inhibit its growth and dissemination. Dynamic contrast enhanced ultrasound (DCE ultrasound) is a quantitative method ...
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Dynamic contrast-enhanced ultrasound of slaughterhouse porcine livers in machine perfusion
Izamis, Maria-Louisa; Efstathiades, Andreas; Keravnou, Christina; Leen, Edward L.; AVERKIOU, MICHALAKIS A. (2014)
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The effect of the phase of transmission on contrast agent echoes
Morgan, K. E.; AVERKIOU, MICHALAKIS A.; Ferrara, K. (1998)Ultrasound contrast agents consist of a gas bubble, encapsulated by a shell for stabilization. The shell dampens the fluctuations in the bubble radius when insonified. The detection of contrast microbubbles during a medical ...
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The effect of the phase of transmission on contrast agent..
Morgan, Karen; AVERKIOU, MICHALAKIS A.; Ferrara, K. (1998)Presents an experimental study which examined the effect of the phase of sonification signal on the ultrasound contrast agent by the bubble echo. Experimental methods
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Effects of air embolism size and location on porcine hepatic microcirculation in machine perfusion
Izamis, Maria-Louisa; Efstathiades, Andreas; Keravnou, Christina; Georgiadou, Soteria; Martins, Paulo N.; AVERKIOU, MICHALAKIS A. (2014)
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Evaluation of the Accuracy of Liver Lesion DCEUS Quantification With Respiratory Gating
Christofides, Damianos; Leen, Edward; AVERKIOU, MICHALAKIS A. (2016)Confidence in the accuracy of dynamic contrast enhanced ultrasound (DCEUS) quantification parameters is imperative for the correct diagnosis of liver lesion perfusion characteristics. An important source of uncertainty in ...
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Harmonic generation with a dual frequency pulse
Keravnou, Christina P.; AVERKIOU, MICHALAKIS A. (2014)Nonlinear imaging was implemented in commercial ultrasound systems over the last 15 years offering major advantages in many clinical applications. In this work, pulsing schemes coupled with a dual frequency pulse are ...
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Article
Harmonic generation with a dual frequency pulse
Keravnou, Christina P.; AVERKIOU, MICHALAKIS A. (2013)Nonlinear imaging was utilized in commercial ultrasound systems over the last 15 years offering major advantages in many clinical applications. In this work, pulsing schemes (pulse inversion, power modulated pulse inversion ...
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High-intensity focused ultrasound-mediated doxorubicin delivery with thermosensitive liposomes
Escoffre, Jean-Michel; Mannaris, Christophoros; Novell, Anthony; Rioc, Laëtitia; Meyre, Marie-Edith; Germain, Matthieu; AVERKIOU, MICHALAKIS A.; Bouakaz, Ayache (2012)Local drug delivery of doxorubicin holds promise to improve the therapeutic efficacy and to reduce toxicity profiles. Here, we investigated the release of doxorubicin from thermosensitive liposomes (Dox-TSL) into human ...
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Image-guided sonoporation in an ex vivomachine perfused porcine liver
Keravnou, Christina; Mannaris, Christophoros; Izamis, Maria-Louisa; AVERKIOU, MICHALAKIS A. (2015)
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Imaging of the Ovine Corpus Luteum Microcirculation with Contrast Ultrasound
Sboros, Vassilis; AVERKIOU, MICHALAKIS A.; Lampaskis, M.; Thomas, D. H.; Silva, N.; Strouthos, Costas; Docherty, J.; McNeilly, A. S. (2011)Ultrasound contrast agents have been the subject of microvascular imaging research. The sheep corpus luteum (CL) is a microvascular tissue that provides a natural angiogenic and antiangiogenic process, which changes during ...
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Imaging the destruction of individual ultrasound contrast microbubbles with diagnostic ultrasound
Guan, Jingfeng; Matula, Thomas J.; AVERKIOU, MICHALAKIS A. (2018)Ultrasound imaging of ultrasound contrast agent fragmentation in a water bath was performed with the color Doppler mode of the HDI 5000 (Phillips Ultrasound). A highly diluted suspension of ultrasound contrast microbubbles ...
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In Vitro localized release of thermosensitive liposomes with ultrasound-induced hyperthermia
Mannaris, Christophoros; Efthymiou, Eleni; Meyre, Marie-Edith; AVERKIOU, MICHALAKIS A. (2013)
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An in vitro system for the study of ultrasound contrast agents using a commercial imaging system
Sboros, V.; Moran, C. M.; Anderson, T.; Gatzoulis, L.; Criton, A.; AVERKIOU, MICHALAKIS A.; Pye, S. D.; McDicken, W. N. (2001)An in vitro system for the investigation of the behaviour of contrast microbubbles in an ultrasound field, that provides a full diagnostic range of settings, is yet to be presented in the literature. The evaluation of a ...
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Indicator Dilution Models for the Quantification of Microvascular Blood Flow With Bolus Administration of Ultrasound Contrast Agents
Strouthos, Costas; Lampaskis, Marios; Sboros, Vassilis; McNeilly, Alan; AVERKIOU, MICHALAKIS A. (2010)Indicator dilution methods have a long history in the quantification of both macro- and microvascular blood flow in many clinical applications. Various models have been employed in the past to isolate the primary pass of ...